Full list of Daley publications:
Please see: Daley Publications on PubMed
Selected publications:
2022
Patel SH, Christodoulou C, Weinreb C, Yu Q, da Rocha EL, Pepe-Mooney BJ,
Bowling S, Li L, Osorio FG, Daley GQ, Camargo FD. Lifelong multilineage
contribution by embryonic-born blood progenitors. Nature. 2022
Jun;606(7915):747-753. doi: 10.1038/s41586-022-04804-z. Epub 2022 Jun 15. PMID:
35705805.
Little M, Morrison SJ, Rossant J, Srivastava D, Daley GQ. Anniversary
reflections: ISSCR presidents on 20 years of progress. Cell Stem Cell. 2022 Jun
2;29(6):876-878. doi: 10.1016/j.stem.2022.05.003. PMID: 35659873.
Morris V, Wang D, Li Z, Marion W, Hughes T, Sousa P, Harada T, Sui SH,
Naumenko S, Kalfon J, Sensharma P, Falchetti M, Vinicius da Silva R, Candelli T,
Schneider P, Margaritis T, Holstege FCP, Pikman Y, Harris M, Stam RW, Orkin SH,
Koehler AN, Shalek AK, North TE, Pimkin M, Daley GQ, Lummertz da Rocha E, Rowe
RG. Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic
leukemia-initiating cells. Cell Rep. 2022 Apr 26;39(4):110752. doi:
10.1016/j.celrep.2022.110752. PMID: 35476984; PMCID: PMC9099058.
Lummertz da Rocha E, Kubaczka C, Sugden WW, Najia MA, Jing R, Markel A,
LeBlanc ZC, Dos Santos Peixoto R, Falchetti M, Collins JJ, North TE, Daley GQ.
CellComm infers cellular crosstalk that drives haematopoietic stem and
progenitor cell development. Nat Cell Biol. 2022 Apr;24(4):579-589. doi:
10.1038/s41556-022-00884-1. Epub 2022 Apr 12. PMID: 35414020.
Wang D, Tanaka-Yano M, Meader E, Kinney MA, Morris V, Lummertz da Rocha E,
Liu N, Liu T, Zhu Q, Orkin SH, North TE, Daley GQ, Rowe RG. Developmental
maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis.
Cell Rep. 2022 Apr 5;39(1):110587. doi: 10.1016/j.celrep.2022.110587. PMID:
35385744; PMCID: PMC9029260.
2021
Missios P, da Rocha EL, Pearson DS, Philipp J, Aleman MM, Pirouz M, Farache
D, Franses JW, Kubaczka C, Tsanov KM, Jha DK, Pepe-Mooney B, Powers JT, Gregory
RI, Lee AS, Dominguez D, Ting DT, Daley GQ. LIN28B alters ribosomal dynamics to
promote metastasis in MYCN-driven malignancy. J Clin Invest. 2021 Nov
15;131(22):e145142. doi: 10.1172/JCI145142. PMID: 34779407; PMCID: PMC8592552.
Yu H, Sun Z, Tan T, Pan H, Zhao J, Zhang L, Chen J, Lei A, Zhu Y, Chen L, Xu
Y, Liu Y, Chen M, Sheng J, Xu Z, Qian P, Li C, Gao S, Daley GQ, Zhang J. rRNA
biogenesis regulates mouse 2C-like state by 3D structure reorganization of peri-
nucleolar heterochromatin. Nat Commun. 2021 Nov 9;12(1):6365. doi:
10.1038/s41467-021-26576-2. PMID: 34753899; PMCID: PMC8578659.
Eser PÖ, Paranal RM, Son J, Ivanova E, Kuang Y, Haikala HM, To C, Okoro JJ,
Dholakia KH, Choi J, Eum Y, Ogino A, Missios P, Ercan D, Xu M, Poitras MJ, Wang
S, Ngo K, Dills M, Yanagita M, Lopez T, Lin M, Tsai J, Floch N, Chambers ES,
Heng J, Anjum R, Santucci AD, Michael K, Schuller AG, Cross D, Smith PD, Oxnard
GR, Barbie DA, Sholl LM, Bahcall M, Palakurthi S, Gokhale PC, Paweletz CP, Daley
GQ, Jänne PA. Oncogenic switch and single-agent MET inhibitor sensitivity in a
subset of EGFR-mutant lung cancer. Sci Transl Med. 2021
Sep;13(609):eabb3738. doi: 10.1126/scitranslmed.abb3738. Epub 2021 Sep 1. PMID:
34516823; PMCID: PMC8627689.
Sun Z, Yu H, Zhao J, Tan T, Pan H, Zhu Y, Chen L, Zhang C, Zhang L, Lei A,
Xu Y, Bi X, Huang X, Gao B, Wang L, Correia C, Chen M, Sun Q, Feng Y, Shen L, Wu
H, Wang J, Shen X, Daley GQ, Li H, Zhang J. LIN28 coordinately promotes
nucleolar/ribosomal functions and represses the 2C-like transcriptional program
in pluripotent stem cells. Protein Cell. 2022 Jul;13(7):490-512. doi:
10.1007/s13238-021-00864-5. Epub 2021 Jul 31. PMID: 34331666; PMCID: PMC9226220.
Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson
DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ,
Daley GQ. Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021
Jul 20;36(3):109408. doi: 10.1016/j.celrep.2021.109408. PMID: 34289374; PMCID:
PMC8371695.
Soto RA, Najia MAT, Hachimi M, Frame JM, Yette GA, Lummertz da Rocha E,
Stankunas K, Daley GQ, North TE. Sequential regulation of hemogenic fate and
hematopoietic stem and progenitor cell formation from arterial endothelium by
Ezh1/2. Stem Cell Reports. 2021 Jul 13;16(7):1718-1734. doi:
10.1016/j.stemcr.2021.05.014. Epub 2021 Jun 17. PMID: 34143974; PMCID:
PMC8282472.
Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M,
Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A,
Goldman SA, Hill L, Hyun I, Isasi R, Kahn J, Kato K, Kim JS, Kimmelman J,
Knoblich JA, Mathews D, Montserrat N, Mosher J, Munsie M, Nakauchi H, Naldini L,
Naughton G, Niakan K, Ogbogu U, Pedersen R, Rivron N, Rooke H, Rossant J, Round
J, Saitou M, Sipp D, Steffann J, Sugarman J, Surani A, Takahashi J, Tang F,
Turner L, Zettler PJ, Zhai X. ISSCR Guidelines for Stem Cell Research and
Clinical Translation: The 2021 update. Stem Cell Reports. 2021 Jun
8;16(6):1398-1408. doi: 10.1016/j.stemcr.2021.05.012. Epub 2021 May 27. PMID:
34048692; PMCID: PMC8190668.
2020
Taylor AM, Macari ER, Chan IT, Blair MC, Doulatov S, Vo LT, Raiser DM, Siva
K, Basak A, Pirouz M, Shah AN, McGrath K, Humphries JM, Stillman E, Alter BP,
Calo E, Gregory RI, Sankaran VG, Flygare J, Ebert BL, Zhou Y, Daley GQ, Zon LI.
Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia. Sci
Transl Med. 2020 Oct 21;12(566):eabb5831. doi: 10.1126/scitranslmed.abb5831.
PMID: 33087503; PMCID: PMC7709865.
Lopes C, Tang Y, Anjo SI, Manadas B, Onofre I, de Almeida LP, Daley GQ,
Schlaeger TM, Rego ACC. Mitochondrial and Redox Modifications in Huntington
Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting.
Front Cell Dev Biol. 2020 Sep 22;8:576592. doi: 10.3389/fcell.2020.576592. PMID:
33072759; PMCID: PMC7536317.
Marion W, Boettcher S, Ruiz-Torres S, Lummertz da Rocha E, Lundin V, Morris
V, Chou S, Zhao AM, Kubaczka C, Aumais O, Zhang Y, Shimamura A, Schlaeger TM,
North TE, Ebert BL, Wells SI, Daley GQ, Rowe RG. An induced pluripotent stem
cell model of Fanconi anemia reveals mechanisms of p53-driven progenitor cell
differentiation. Blood Adv. 2020 Oct 13;4(19):4679-4692. doi:
10.1182/bloodadvances.2020001593. PMID: 33002135; PMCID: PMC7556119.
Frame JM, Kubaczka C, Long TL, Esain V, Soto RA, Hachimi M, Jing R, Shwartz
A, Goessling W, Daley GQ, North TE. Metabolic Regulation of Inflammasome
Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production.
Dev Cell. 2020 Oct 26;55(2):133-149.e6. doi: 10.1016/j.devcel.2020.07.015. Epub
2020 Aug 17. PMID: 32810442; PMCID: PMC8008739.
Franses JW, Philipp J, Missios P, Bhan I, Liu A, Yashaswini C, Tai E, Zhu H,
Ligorio M, Nicholson B, Tassoni EM, Desai N, Kulkarni AS, Szabolcs A, Hong TS,
Liss AS, Fernandez-Del Castillo C, Ryan DP, Maheswaran S, Haber DA, Daley GQ,
Ting DT. Pancreatic circulating tumor cell profiling identifies LIN28B as a
metastasis driver and drug target. Nat Commun. 2020 Jul 3;11(1):3303. doi:
10.1038/s41467-020-17150-3. PMID: 32620742; PMCID: PMC7335061.
Tao T, Shi H, Mariani L, Abraham BJ, Durbin AD, Zimmerman MW, Powers JT,
Missios P, Ross KN, Perez-Atayde AR, Bulyk ML, Young RA, Daley GQ, Look AT.
LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma
through binding to ZNF143 at target gene promotors. Proc Natl Acad Sci U S A.
2020 Jul 14;117(28):16516-16526. doi: 10.1073/pnas.1922692117. Epub 2020 Jun 29.
PMID: 32601179; PMCID: PMC7368283.
Donoff RB, Daley GQ. Oral health care in the 21st century: It is time for
the integration of dental and medical education. J Dent Educ. 2020
Sep;84(9):999-1002. doi: 10.1002/jdd.12191. Epub 2020 May 20. PMID: 32436218.
Chen MJ, Lummertz da Rocha E, Cahan P, Kubaczka C, Hunter P, Sousa P, Mullin
NK, Fujiwara Y, Nguyen M, Tan Y, Landry S, Han A, Yang S, Lu YF, Jha DK, Vo LT,
Zhou Y, North TE, Zon LI, Daley GQ, Schlaeger TM. Transcriptome Dynamics of
Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a
Reporter System. Stem Cell Reports. 2020 May 12;14(5):956-971. doi:
10.1016/j.stemcr.2020.03.020. Epub 2020 Apr 16. PMID: 32302558; PMCID:
PMC7220988.
Truog RD, Mitchell C, Daley GQ. The Toughest Triage - Allocating Ventilators
in a Pandemic. N Engl J Med. 2020 May 21;382(21):1973-1975. doi:
10.1056/NEJMp2005689. Epub 2020 Mar 23. PMID: 32202721.
2019
Yu C, Wang L, Rowe RG, Han A, Ji W, McMahon C, Baier AS, Huang YC, Marion W,
Pearson DS, Kruse AC, Daley GQ, Wu H, Sliz P. A nanobody targeting the
LIN28:let-7 interaction fragment of TUT4 blocks uridylation of let-7. Proc Natl
Acad Sci U S A. 2020 Mar 3;117(9):4653-4663. doi: 10.1073/pnas.1919409117. Epub
2020 Feb 14. PMID: 32060122; PMCID: PMC7060709.
Lundin V, Sugden WW, Theodore LN, Sousa PM, Han A, Chou S, Wrighton PJ, Cox
AG, Ingber DE, Goessling W, Daley GQ, North TE. YAP Regulates Hematopoietic Stem
Cell Formation in Response to the Biomechanical Forces of Blood Flow. Dev Cell.
2020 Feb 24;52(4):446-460.e5. doi: 10.1016/j.devcel.2020.01.006. Epub 2020 Feb
6. PMID: 32032546; PMCID: PMC7398148.
Kinney MA, Vo LT, Frame JM, Barragan J, Conway AJ, Li S, Wong KK, Collins
JJ, Cahan P, North TE, Lauffenburger DA, Daley GQ. A systems biology pipeline
identifies regulatory networks for stem cell engineering. Nat Biotechnol. 2019
Jul;37(7):810-818. doi: 10.1038/s41587-019-0159-2. Epub 2019 Jul 1. Erratum in:
Nat Biotechnol. 2019 Aug;37(8):962. PMID: 31267104; PMCID: PMC7235931.
Blau HM, Daley GQ. Stem Cells in the Treatment of Disease. N Engl J Med.
2019 May 2;380(18):1748-1760. doi: 10.1056/NEJMra1716145. Erratum in: N Engl J
Med. 2019 Aug 29;381(9):890. PMID: 31042827.
Rowe RG, Daley GQ. Induced pluripotent stem cells in disease modelling and
drug discovery. Nat Rev Genet. 2019 Jul;20(7):377-388. doi:
10.1038/s41576-019-0100-z. PMID: 30737492; PMCID: PMC6584039.
Rowe RG, Lummertz da Rocha E, Sousa P, Missios P, Morse M, Marion W,
Yermalovich A, Barragan J, Mathieu R, Jha DK, Fleming MD, North TE, Daley GQ.
The developmental stage of the hematopoietic niche regulates lineage in
MLL-rearranged leukemia. J Exp Med. 2019 Mar 4;216(3):527-538. doi:
10.1084/jem.20181765. Epub 2019 Feb 6. PMID: 30728174; PMCID: PMC6400531.
Robinton DA, Chal J, Lummertz da Rocha E, Han A, Yermalovich AV, Oginuma M,
Schlaeger TM, Sousa P, Rodriguez A, Urbach A, Pourquié O, Daley GQ. The
Lin28/let-7 Pathway Regulates the Mammalian Caudal Body Axis Elongation Program.
Dev Cell. 2019 Feb 11;48(3):396-405.e3. doi: 10.1016/j.devcel.2018.12.016. Epub
2019 Jan 17. PMID: 30661985.
Daley GQ, Lovell-Badge R, Steffann J. After the Storm - A Responsible Path
for Genome Editing. N Engl J Med. 2019 Mar 7;380(10):897-899. doi:
10.1056/NEJMp1900504. Epub 2019 Jan 16. PMID: 30649993.
Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA,
Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ. Lin28 and let-7
regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan
11;10(1):168. doi: 10.1038/s41467-018-08127-4. Erratum in: Nat Commun. 2020 Mar
9;11(1):1327. PMID: 30635573; PMCID: PMC6329821.
Stolla MC, Catherman SC, Kingsley PD, Rowe RG, Koniski AD, Fegan K, Vit L,
McGrath KE, Daley GQ, Palis J. Lin28b regulates age-dependent differences
in murine platelet function. Blood Adv. 2019 Jan 8;3(1):72-82. doi:
10.1182/bloodadvances.2018020859. PMID: 30622145; PMCID: PMC6325299.